Graber NeuroMuscular Physiology Laboratory

We examine the effect of advancing age on muscle and the molecular mechanisms that underlie age-associated loss of physical function/performance primarily by utilizing pre-clinical models of aging, sarcopenia, frailty and exercise. Our basic science and translational/reverse translational approaches encompass: standard biochemical wetlab techniques such as Western Blotting, q-rt-PCR, and enzymatic assays; immunohistochemistry and imaging; behavioral/functional testing (e.g. rotarod, grip strength, treadmill, voluntary wheel running, etc.); in vitro/ex vivo and in vivo contractile physiology; and ‘omics technologies such as transcriptomics using RNAseq Next Generation Sequencing, and proteomics using tandem mass spectrometry. Our laboratory is housed within the Brody School of Medicine, a short walk from the Health Sciences Building, the College of Allied Health Sciences, and the Physical Therapy Department.

We invite you to browse our website, check out our current research projects, and to get in touch with us via the “Contact Us” page if you have questions, would like to collaborate, or are interested in joining our research group–we are always in search of excellent researchers to work with. We are currently actively recruiting for a PhD student to join us.